
SportsLine model targets 25-1 payout in NFL Week 2 parlay
A computer model that has simulated the 14-game slate 10,000 times identifies a five-leg parlay with significant odds, headlined by a Seahawks spread cover.
Event
SportsLine's computer model, which has simulated Week 2 NFL games 10,000 times, has identified a five-leg parlay with odds of nearly 25-1. The model, currently on a 53-39 run for top-rated picks since 2024, favours the Seattle Seahawks to cover the spread against the Arizona Cardinals. The article highlights several other matchups, including the Minnesota Vikings versus the Chicago Bears and the Los Angeles Rams versus the New York Giants, while noting that Sam Darnold is out for Seattle due to injury.
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A computer model that has simulated the 14-game slate 10,000 times identifies a five-leg parlay with significant odds, headlined by a Seahawks spread cover.
Background
SportsLine’s computer model, which has simulated the 14-game Week 2 NFL slate 10,000 times, has released its top-rated betting picks for the 2026 season. The model, which holds a 53-39 record for top-rated picks since 2024, identifies a five-leg parlay with odds of nearly 25-1. A key selection involves the Seattle Seahawks covering the -3.5 point spread against the Arizona Cardinals, a matchup where Seattle has won their last nine meetings. The prediction comes amid roster changes for Seattle, with Sam Darnold ruled out due to a glute injury and Drew Lock set to start. Other notable matchups in the model’s analysis include the Minnesota Vikings versus the Chicago Bears and the Los Angeles Rams versus the New York Giants.
SportsLine’s computer model, which has simulated the 14-game Week 2 NFL slate 10,000 times, has released its top-rated betting picks for the 2026 season. The model, which holds a 53-39 record for top-rated picks since 2024, identifies a five-leg parlay with odds of nearly 25-1. A
Fact cards
Key entities: SportsLine, NFL, Seattle Seahawks, Arizona Cardinals, CBS Sports, Houston Texans.
What are the odds for the SportsLine Week 2 parlay? The five-leg parlay offers odds of nearly 25-1. Who is starting for the Seattle Seahawks in Week 2? Drew Lock is set to start, as Sam Darnold is out with a glute injury. What is the model’s record for top-rated picks? The model
CBS Sports | https://www.cbssports.com/betting/news/2026-week-2-nfl-parlay-picks-predictions-bets | published 2026-09-17T14:40:57.000Z | primary source | CBS Sports | https://www.cbssports.com/betting/news/2026-week-2-nfl-score-predictions-picks-best-bets | published 2026-09-17T1
2024-09-01: SportsLine model begins tracking top-rated picks, currently holding a 53-39 record. 2026-09-10: Seattle Seahawks defeat New England Patriots 13-10 in the season opener; Sam Darnold sustains a glute injury. 2026-09-17: SportsLine releases Week 2 predictions, identifyin
Timeline
SportsLine model begins tracking top-rated picks, currently holding a 53-39 record.
Seattle Seahawks defeat New England Patriots 13-10 in the season opener; Sam Darnold sustains a glute injury.
SportsLine releases Week 2 predictions, identifying a five-leg parlay with nearly 25-1 odds.
NFL Week 2 slate commences, featuring 14 games including Seahawks vs Cardinals.
FAQ
The five-leg parlay offers odds of nearly 25-1.
Drew Lock is set to start, as Sam Darnold is out with a glute injury.
The model is on a 53-39 run for top-rated picks since 2024.
The model simulated each of the 14 games 10,000 times.
The model predicts the Houston Texans will defeat the Cincinnati Bengals 27-21.
Each matchup was simulated 10,000 times.
The model is on a 53-39 run for top-rated picks since 2024.
The highest total is 50.5 for the Commanders vs. Cowboys game.