49ers and Rams set for NFL opener at Melbourne Cricket Ground
The Rams are listed as 3.5-point favourites against the 49ers, with CBS Sports analyst Micah Roberts backing the total to exceed 48.5 points.
The San Francisco 49ers and Los Angeles Rams will meet at Melbourne Cricket Ground on Thursday in an NFL Week 1 season opener, bringing two NFC West rivals to Australia.
Kickoff is scheduled for 8:35 p.m. ET. The Rams are listed as 3.5-point favourites, while the over-under for total points is 48.5.
CBS Sports betting analyst Micah Roberts has recommended the total go over 48.5. The selection is an attributed betting opinion, and the published odds and recommendation may change before kickoff.
CBS Sports reports that both teams finished the 2025 season with 12-5 records, tied for second in the NFC West. The publication describes the Rams and 49ers as recent Super Bowl contenders.
The CBS Sports preview cites the teams’ 2025 offensive figures in support of Roberts’ recommendation. It says Los Angeles led the league in total yards and average points, while San Francisco ranked seventh in total yards and 10th in points.
CBS Sports also identifies Rams quarterback Matthew Stafford, reported as the 2025 league MVP, and San Francisco’s Brock Purdy and Christian McCaffrey as key players in the matchup. The publication says Roberts has a 19-5 record on recent picks involving the 49ers, a claim presented by CBS Sports and not independently verified in the supplied material.
